Table 2. Adjusted odds ratio of aneurysm size and prognosis by the NLR and status of aneurysm rupture.
Model 1* | Model 2† | ||||||
Characteristic | Groups | n | Events, n (%) | Adjusted OR (95% CI) | P Value | Adjusted OR (95% CI) | P Value |
Aneurysm size>10mm | NLR<4 with uIAs | 363 | 86 (23.7) | Reference | Reference | ||
NLR≥4 with uIAs | 21 | 10 (47.6) | 2.79 (1.14-6.85) | 0.025 | 2.78 (1.11-6.98) | 0.030 | |
NLR<4 with rIAs | 76 | 12 (15.8) | Ref | Ref | |||
NLR≥4 with rIAs | 72 | 5 (6.9) | 0.44 (0.14-1.33) | 0.146 | 0.53 (0.16-1.74) | 0.295 | |
Aneurysm Rupture | NLR<4 | 439 | 76 (17.3) | Reference | Reference | ||
NLR≥4 | 93 | 72 (77.4) | 17.07 (9.80-29.72) | <0.001 | 18.46 (10.04-33.92) | <0.001 | |
Poor outcome | NLR<4 with uIAs | 363 | 4 (1.1) | Reference | Reference | ||
NLR≥4 with uIAs | 21 | 1 (4.8) | 6.39 (0.62-66.01) | 0.119 | 8.58 (0.37-198.94) | 0.180 | |
NLR<4 with rIAs | 76 | 7 (9.2) | Reference | Reference | |||
NLR≥4 with rIAs | 72 | 19 (26.4) | 3.16 (1.22-8.21) | 0.018 | 3.29 (1.07-10.15) | 0.038 | |
DCI | NLR<4 with rIAs | 76 | 11 (14.5) | Reference | Reference | ||
NLR≥4 with rIAs | 72 | 24 (33.3) | 2.85 (1.26-6.45) | 0.012 | 2.75 (1.12-6.73) | 0.027 |
rIAs, ruptured intracranial aneurysms; uIAs, unruptured intracranial aneurysms; NLR, neutrophil-lymphocyte ratio; and DCI, delayed cerebral ischemia; CI, confidence interval; OR, odds ratio.
*Model 1: adjusted for age and sex.
†Model 2:
Size: adjusted for model 1+ history of stroke, hypertension, hyperlipidemia, diabetes mellitus, heart disease, smoking status, and aneurysm location.
Aneurysm rupture: adjusted for model 1+ history of stroke, hypertension, hyperlipidemia, diabetes mellitus, heart disease, smoking status, aneurysm location, and aneurysm size.
Poor outcome: adjusted for model 1+ history of stroke, hypertension, hyperlipidemia, diabetes mellitus, heart disease, smoking status, aneurysm location, aneurysm size, treatment modality, and modified Fisher grade.
DCI: adjusted for model 1+ history of stroke, hypertension, hyperlipidemia, diabetes mellitus, heart disease, smoking status, aneurysm location, aneurysm size, treatment modality, and modified Fisher grade.