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. 2013 Sep 13;12(4):469–483. doi: 10.1111/iwj.12142

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© 2013 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/3.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Time‐course study of the antimicrobial efficacy of antimicrobial ointments/gels on PAO1 cultured for 3 days on porcine explants (without antibiotic pre‐treatment) prior to dressing exposure. Single application of dressing with bacterial load determined after 1, 12, 24, 48 and 72 hours of exposure to Silvasorb ^® gel (polyacrylate–AgCl), PHMB gel (Prontosan^®), 50% cadexomer iodine (Iodosorb ^®), 100% cadexomer iodine (Iodoflex™), cadexomer (Cadesorb ^®) or cotton gauze. Pairwise statistical comparisons of wet gauze verses the following: Iodoflex P ≤ 0·001 at all time points; Prontosan P ≤ 0·001 at 12 hours; Cadesorb P ≤ 0·001 at 12 and 24 hours; Iodosorb P ≤ 0·001 at all times points except 1 hour; Silvasorb P ≤ 0·001 at all time points except 1 hour.