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. 2013 Sep 13;12(4):469–483. doi: 10.1111/iwj.12142

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© 2013 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/3.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Time‐course study of PHMB gel (Prontosan^®) bactericidal/bacteriostatic efficacy on PAO1 that was cultured for 0–3 days on porcine explants (without antibiotic pre‐treatment) prior to dressing exposure. Single application of Prontosan or cotton gauze with bacterial load determined after 1, 12 and 24 hours of exposure. No statistically significant difference was found between exposure times within each level of biofilm maturity. No statistical difference was found between treatments at each level of biofilm maturity.