Table 1.

Institutional recommendations on the concentration, fluid delivery, soak time and cycle frequency of polyhexanide, acetic acid and povidone‐iodine for use with NPWTi

Solution	Concentration	Fluid delivery	Soak time	Cycle frequency
Polyhexanide	Concentration of 0·1% polyhexanide or 0·04% polyhexanide. On cartilage at the wound ground, the effective concentration of polyhexanide should be reduced to 0·005% to avoid adverse effects.	Amount of instilled fluid depends on wound volume. User‐selected instillation volume is controlled by the device.	20 minutes	4–8 times per day
Acetic acid	Concentrations between 0·25% and 1% are recommended.	Amount of instilled fluid depends on wound volume. User‐selected instillation volume is controlled by the device.	20 minutes	4–8 times per day
Povidone‐iodine	A combination of ethanol/propan‐2‐ol and povidone‐iodine [e.g. available as 100 ml solution, 3·24 g povidone‐iodine (this means 0·324%), 38·9 g isopropanol and 38·9 g ethanol] is the first‐choice antiseptic in the treatment of stabbing wounds at risk of infection with HBV, HCV or HIV and should be applied after bleeding has been encouraged. The same applies to the initial treatment of bite wounds.	Amount of instilled fluid depends on wound volume. User‐selected instillation volume is controlled by the device.	20 minutes	4–8 times per day

NPWTi, negative pressure wound therapy with instillation; HBV, hepatitis B virus; HCV, hepatitis C virus; HIV, human immunodeficiency virus.