Table 2.

General scheme of the trial

Study time	Clinical time	Activity	Description
T0	0	Enrolment	Scar clinical photography
T1	7–28 days from T0	Surgery	Scar removal
			Surrounding tissues release
			Scar biopsy
			Wound bed clinical photography  Hyalomatrix® inlay
T2	Every 3 days from T1	Post‐operative observation	Dressing care
T3	13–27 days from T1	Surgery	Silicone layer removal
			Regenerated derma‐like biopsy
			Wound bed photography
			Split skin graft
T4	Within 2 months from T1	Post‐operative and primary conclusive observation	Dressing care
			Clinical post‐operative photography
T5	10–13 months from T1	Conclusive follow‐up	Reconstructed area photography
			Grafted skin biopsy (three cases only)