Table 2.
Microvascular blood flow in the wound edge during negative pressure wound therapy at various pressures using pathogen‐binding mesh, foam and gauze, measured using laser Doppler velocimetry
| −40 mmHg | −60 mmHg | −80 mmHg | −120 mmHg | ||
|---|---|---|---|---|---|
| Measurements were performed 0·5 cm from the wound edge | |||||
| Pathogen‐binding mesh | −12 ± 6% | −19 ± 6% | −21 ± 6% | −15 ± 8% | n.s. |
| Gauze | −13 ± 3% | −17 ± 4% | −22 ± 5% | −24 ± 4% | n.s. |
| Foam | −27 ± 5% | −31 ± 4% | −33 ± 4% | −36 ± 4% | n.s. |
| Foam versus gauze or mesh P < 0·05 | Foam versus gauze or mesh P < 0·05 | Foam versus gauze or mesh P < 0·05 | Foam versus gauze or mesh P < 0·05 | ||
| Measurements were performed 2·5 cm from the wound edge | |||||
| Pathogen‐binding mesh | +45 ± 18% | +54 ± 18% | +60 ± 17% | +61 ± 16% | n.s. |
| Gauze | +38 ± 6% | +50 ± 9% | +50 ± 8% | +54 ± 9% | n.s. |
| Foam | +40 ± 8% | +58 ± 15% | +58 ± 14% | +54 ± 12% | n.s. |
| n.s. | n.s. | n.s. | n.s. | ||
Microvascular blood flow is expressed as percent change relative to baseline values. Values are presented as means ± standard error of the mean (n = 8).