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. 2012 Jun 4;10(4):441–454. doi: 10.1111/j.1742-481X.2012.01003.x

Figure 7.

Figure 7

Immunohistological localization of endothelial nitric oxide synthase (eNOS) and interlukin 6 (IL‐6) in sulphur mustard (SM) (5 or 10 mg/kg, diluted in acetone) treated mouse skin sections taken at various time intervals. Bar = 25 µm. (A) Negative control (without eNOS primary antibody). (B) eNOS expression at 72 hours after SM (5 mg/kg) treatment showing immunoreactivity in infiltrated inflammatory cells and blood vessel endothelium (circles). (C) Negative control (without IL‐6 primary antibody). (D) 3 hours after SM (5 mg/kg) treatment showing IL‐6 positive signals by epidermal cells, hair follicle (arrow) and few transmigrated inflammatory cells. (E) 168 hours (SM 5 mg/kg) showing weak IL‐6 immunoreactivity compared to (D). (F) 168 hours (SM 10 mg/kg) showing mild IL‐6 immunosignals in upper part of dermis adnexa only (arrow). Note decrease in intensity as compared to (D).