Figure 8.

Immunohistological localization of fibroblast growth factor (FGF) in sulphur mustard (SM) (5 or 10 mg/kg, diluted in acetone) treated mouse skin sections taken at various time intervals. Bar = 25 µm. (A) Negative control (without primary FGF antibody). (B) 0 hours after SM (10 mg/kg) treatment showing similar FGF immunoreactivity as shown by (A). (C) 48 hours after SM (5 mg/kg) exposure showing mild streaks of FGF immunoreactivity (arrow) diffused throughout the dermis. Note increase in immunorectivity of FGF as compared to (B). (D) 48 hours after SM (10 mg/kg) exposure showing mild streaks of FGF immunoreactivity (arrow) similar to (C). (E) 168 hours (SM 5 mg/kg) showing enhanced FGF immunoreactivity (arrow) compared to (C). (F) 168 hours (SM 10 mg/kg) showing moderate FGF (arrow) expression that was more intense than (D) and similar to (E).