Table 2.
The efficacy [mean ZOI (mm)] of antibiotics aztreonam (ATM30) and levofloxacin (LVX5) on a representative sample of Gram‐negative wound isolates grown at pH 5·5 and 7 in the quasi/non biofilm state
| Isolate | Wound type | Number | Antibiotic Mean ZOI (mm) | |||
|---|---|---|---|---|---|---|
| ATM30 | LVX5 | |||||
| pH 7 (± SE) | pH 5·5 (± SE) | pH 7 (± SE) | pH 5·5 (±SE) | |||
| Gram‐negative rods | Chronic | 4 | 30·0 ± 3·0 | 27 ± 3·0 | 31 ± 2·0 | 29 ± 4·0 |
| Acinetobacter baumannii | Burn | 4 | 8·9 ± 3·0 | 11·0 ± 4·0 | 12·5 ± 6·2 | 7·6 ± 7·6 |
| Enterobacter sp | Burn | 5 | 27·3 ± 8·5 | 24·3 ± 7·6 | 26·2 ± 8·5 | 18·3 ± 6·8 |
| Escherichia coli | Burn | 6 | 33·1 ± 1·0 | 28·7 ± 1·2 | 28·9 ± 7·0 | 18·3 ± 8·0 |
| Klebsiella sp | Burn | 4 | 33·4 ± 0·8 | 20·1 ± 7·1 | 31·8 ± 0·7 | 22·1 ± 1·6 |
| Proteus mirabilis | Burn | 3 | 41 ± 0·3 | 41 ± 1·7 | 30·3 ± 7·8 | 31·2 ± 9·1 |
| Pseudomonas aeruginosa | Chronic | 2 | 18 ± 6·0 | 14·25 ± 14·0 | 12 ± 12·0 | 14 ± 14·0 |
| Burn | 5 | 19·6 ± 1·4 | 19·8 ± 5·0 | 18·4 ± 2·2 | 18·1 ± 5·0 | |
SE, standard error; ZOI, zone of inhibition.