Table 1.
Grade of wound reepithelialisation 2, 7 and 14 days after surgical intervention (Pearson chi‐square test)
| Day | Group | Total | Histopathologic scale to evaluate reepithelialisation: n (%) | |||||
|---|---|---|---|---|---|---|---|---|
| Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | P value | |||
| 2 | Apigenin | 16 | 1 (6·25) | 12 (75) | 3 (18·75) | 0 (0) | 0 (0) | 0·022 |
| PLX | 16 | 3 (18·75) | 3 (18·75) | 9 (56·25) | 1 (6·25) | 0 (0) | ||
| Vehicle | 16 | 6 (37·50) | 8 (50) | 2 (12·50) | 0 (0) | 0 (0) | ||
| Control | 16 | 5 (31·25) | 8 (50) | 3 (18·75) | 0 (0) | 0 (0) | ||
| 7 | Apigenin | 16 | 0 (0) | 0 (0) | 0 (0) | 11 (68·75) | 5 (31·25) | 0·040 |
| PLX | 16 | 0 (0) | 0 (0) | 0 (0) | 9 (56·25) | 7 (43·75) | ||
| Vehicle | 16 | 0 (0) | 0 (0) | 1 (6·25) | 14 (87·50) | 1 (6·25) | ||
| Control | 16 | 0 (0) | 0 (0) | 3 (18·75) | 11 (68·75) | 2 (12·50) | ||
| 14 | Apigenin | 16 | 0 (0) | 0 (0) | 0 (0) | 2 (12·50) | 14 (87·50) | 0·751 |
| PLX | 16 | 0 (0) | 0 (0) | 0 (0) | 2 (12·50) | 14 (87·50) | ||
| Vehicle | 16 | 0 (0) | 0 (0) | 0 (0) | 4 (25) | 12 (75) | ||
| Control | 16 | 0 (0) | 0 (0) | 0 (0) | 3 (18·75) | 13 (81·25) | ||
Grade 0, reepithelialisation at the edge of the wound; Grade 1, reepithelialisation covering less than half of the wound; Grade 2, reepithelialisation covering more than half of the wound; Grade 3, reepithelialisation covering the entire wound with irregular thickness; Grade 4, reepithelialisation covering the entire wound with normal thickness.