Fig. 6.
Effect of NHE inhibition on intracellular pH and actin dynamics during restitution in mouse gastroids in vitro. A single gastric organoid epithelial cell was photodamaged (PD) in the presence of EIPA (red, n = 7) or DMSO only (Control, black, n = 7). Compiled results showing time course of damaged area (a), with these results replicated in subsequent panels to provide a reference time frame. b Time course of pHi measured in migrating cells repairing damage. C Time course of GFP-actin intensity measured in the lateral spaces of migrating cells as previously [33]. Mean ± SEM