Table 3.
Variables | 90‐day mortality risk Adjusted hazard ratio N = 5870 | 90‐ to 180‐day mortality risk Adjusted hazard ratio N = 3204 |
---|---|---|
Demographic characteristics | ||
Age (years) | 1·02 (1·02–1·02), P < 0·001 | 1·02 (1·01–1·12), P < 0·001 |
Male sex | 1·15 (1·06–1·24), P = 0·001 | 1·37 (1·16–1·62), P < 0·001 |
Black race* | 0·92 (0·84–1·01), P = 0·081 | 0·97 (0·80–1·17), P = 0·799 |
Hispanic race* | 1·13 (1·01–1·26), P = 0·032 | 1·61 (1·30–2·00), P < 0·001 |
Clinical characteristics | ||
DRG weight | – | 1·06 (1·04–1·08), P < 0·001 |
Systemic infection or fever | 1·50 (1·37–1·63), P < 0·001 | – |
Laboratory values | ||
Albumin (g/dl) | 0·57 (0·53–0·60), P < 0·001 | 0·69 (0·61–0·79), P < 0·001 |
White blood cells (k/µl) | 1·00 (1·00–1·01), P = 0·046 | – |
Haematocrit (%) | 1·01 (1·01–1·02), P = 0·001 | – |
Sodium (mEq/l)** | – | – |
Glucose (mg/dl) | – | – |
Estimated glomerular filtration rate on admission (ml/min/1·73 m2) | – | – |
Comorbid disease | ||
Diabetes | 1·31 (1·12–1·55), P = 0·001 | 1·63 (1·14–2·34), P = 0·007 |
Congestive heart failure | 1·35 (1·25–1·47), P < 0·001 | 1·26 (1·07–1·50), P = 0·007 |
Chronic renal failure | 1·46 (1·35–1·59), P < 0·001 | 1·34 (1·12–1·60), P = 0·001 |
Any liver disease | 1·21 (1·07–1·36), P = 0·002 | – |
Human immunodeficiency virus/AIDS | 1·40 (1·09–1·79), P = 0·008 | – |
Dementia | – | – |
Cerebrovascular disease | 1·17 (1·06–1·29), P = 0·002 | – |
Hemiplegia/paraplegia | – | – |
Myocardial infarction | 1·35 (1·20–1·52), P < 0·001 | – |
Peripheral vascular disease | – | – |
Chronic pulmonary disease | – | – |
Rheumatic disease | – | – |
Peptic ulcer | – | 1·50 (1·01–2·23), P = 0·045 |
Any malignancy** | – | 1·62 (1·23–2·12), P < 0·001 |
Metastatic cancer | 2·48 (2·06–2·99), P < 0·001 | 1·53 (1·06–2·22), P = 0·024 |
Interaction terms | ||
Systemic infection/fever – metastatic cancer | 0·54 (0·41–0·72), P < 0·001 |
*Hazard ratios for race were compared with patients with ‘White’ or ‘Other’ race. **90‐day model: stratified for any malignancy and for sodium.