Figure 3.

Reduced purine precursors correlates with increased wound severity. (A) A scatter plot of the levels of purine precursors versus PUSH scores. (B) Levels were expressed as concentration of the precursor purines (sum totals of adenosine, inosine, xanthine and hypoxanthine) (µM/mg of total protein) ± SEM. The amount of precursor purines was significantly higher (p < 0·0001) in the lower PUSH score group (3–9, n = 12) compared to the clinically worse ulcers (10–16, n = 17). Statistical significance was determined by the Mann–Whitney non parametric test.