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. Author manuscript; available in PMC: 2021 Mar 11.
Published in final edited form as: Am J Ophthalmol. 2019 Dec 14;214:172–187. doi: 10.1016/j.ajo.2019.12.006

FIGURE 1.

FIGURE 1.

Overview of acquisition, processing, and analysis workflow. Acquisition and processing yield optical coherence tomography (OCT) data that are used to trace the baseline and follow-up geographic atrophy (GA) margins and OCT angiography (OCTA) data that are used to generate baseline and follow-up registration fiducials and baseline choriocapillaris (CC) OCTA slabs. The baseline CC OCTA slabs, along with the baseline GA geometry are used to perform CC impairment analysis at global, zonal, and local scales. The baseline and follow-up GA geometries are used to perform GA growth analysis at global and local scales. The CC impairment metrics and the GA growth metrics are then correlated to assess potential relationships. Details of acquisition, processing, and analysis are provided in the Methods section, and an overview of the CC impairment and GA growth metric is shown in Table 1.