Table 4.

Prognostic factors in malaria patients with multi-organ dysfunction syndrome^a

Parameter	Number of malaria patients with MODS (n=108)		P
	Survivors (n=102)	Nonsurvivors (n=6)
Age (years)	38.56±16.83	43.83±16.99	0.457
Durations of illness before initiating antimalarial treatment (days)	6.81±5.02	7.5±3.71	0.741
Hemoglobin (g/dL)	9.97±2.65	10.62±2.46	0.559
TLC (/cumm)	7108.90±4116.66	10,485±4418.96	0.054
Platelet count (thousand/cumm)	37.37±53.30	103.58±51.98	<0.001
Random blood glucose (mg/dL)	130.13±71.79	128.67±77.42	0.961
Serum total bilirubin (mg/dL)	4.82±5.51	3.92±5.17	0.697
Serum alanine aminotransferase (U/L)	47.33±29.74	45±31.18	0.852
Serum aspartate aminotransferase (U/L)	70.67±47.60	57.67±49.33	0.517
Blood urea nitrogen (mg/dL)	43.15±37.72	44.05±40.34	0.955
Serum creatinine (mg/dL)	2.18±2.52	2.67±2.70	0.645
Serum sodium (mmol/L)	135.08±9.79	137.78±10.75	0.514
Serum potassium (mmol/L)	4.16±0.68	3.73±0.73	0.136
Serum bicarbonate (mmol/L)	18.91±4.93	18.52±5.35	0.851
SOFA score on admission	7.98±3.87	11.67±3.88	0.025
SOFA score on day 3*	5.34±3.18	11.67±3.88	<0.001
SOFA score on discharge/expiry*	2.61±2.04	12±3	<0.001

^aData are mean±SD. SOFA score: Sequential organ failure assessment score, *SOFA score on day 3 and at discharge/expiry was calculated for 105 MODS patients (102 MODS-survivors and 3 MODS-nonsurvivors). SD: Standard deviation, MODS: Multi-organ dysfunction syndrome, TLC: Total leucocyte count