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. 2021 Feb 6;8(3):548–557. doi: 10.1002/acn3.51276

Table 2.

Descriptive statistics on age and HINE‐2 scores subdivided by age group and Dubowitz decimal classification.

HINE ‐II Scores Changes
Baseline 12 months 24 months 0–12 P‐value 12–24 P‐value 0–24 P‐value
ALL ALL (n:68) Mean ± SD 0.88 ± 1.33 2.75 ± 3.87 3.5 ± 4.96 1.87 ± 3.18 <0.001 0.75 ± 1.92 <0.001 2.62 ± 4.39 <0.001
Min; Max 0; 5 0; 16 0; 18 −3; 12 −3; 8 −3; 17
1.1 (n:7) Mean ± SD 0.14 ± 0.38 1.29 ± 3.4 1.29 ± 3.4 1.14 ± 3.02 0 ± 0 1.14 ± 3.02
Min; Max 0; 1 0; 9 0; 9 0; 8 0; 0 0; 8
1.5 (n:36) Mean ± SD 0.22 ± 0.64 1.5 ± 2.81 2.31 ± 4.48 1.28 ± 2.75 0.81 ± 1.92 2.08 ± 4.39
Min; Max 0; 3 0; 10 0; 18 −3; 9 0; 8 −3; 17
1.9 (n:25) Mean ± SD 2.04 ± 1.46 4.96 ± 4.4 5.84 ± 5.23 2.92 ± 3.62 0.88 ± 2.17 3.8 ± 4.56
Min; Max 0; 5 0; 16 0; 16 −1; 12 −3; 7 −2; 12
<210 days ALL (n:7) Mean ± SD 0.86 ± 0.69 7.43 ± 3.36 10.86 ± 3.58 6.57 ± 3.21 0.002 3.43 ± 2.99 0.023 10.00 ± 3.46 <0.001
Min; Max 0; 2 2; 12 8; 18 2; 11 0; 8 7; 17
1.1 (n:1) Mean ± SD 1 ± N/A 9 ± N/A 9 ± N/A 8 ± N/A 0 ± N/A 8 ± N/A
Min; Max 1; 1 9; 9 9; 9 8; 8 0; 0 8; 8
1.5 (n:5) Mean ± SD 0.80 ± 0.84 6.20 ± 3.03 11 ± 4.24 5.40 ± 2.88 4.80 ± 2.28 10.20 ± 4.09
Min; Max 0; 1 2; 10 8; 18 2; 9 2; 8 7; 17
1.9 (n:1) Mean ± SD 1 ± N/A 12 ± N/A 12 ± N/A 11 ± N/A 0 ± N/A 11 ± N/A
Min; Max 1; 1 12; 12 12; 12 11; 11 0; 0 11; 11
<2 years ALL (n:23) Mean ± SD 1.39 ± 1.62 4.35 ± 4.81 5.73 ± 6.09 2.95 ± 3.44 <0.001 1.39 ± 2.14 0.005 4.35 ± 4.82 <0.001
Min; Max 0; 5 0; 16 0; 19 0; 12 0; 7 0; 15
1.1 (n:3) Mean ± SD 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0
Min; Max 0; 0 0; 0 0; 0 0; 0 0; 0 0; 0
1.5 (n:11) Mean ± SD 0.45 ± 0.69 2.00 ± 2.89 2.45 ± 3.85 1.55 ± 2.54 0.45 ± 1.21 2.00 ± 3.49
Min; Max 0; 2 0; 8 0; 12 0; 7 0; 4 0; 11
1.9 (n:9) Mean ± SD 3 ± 1.32 8.67 ± 4.18 11.67 ± 4.09 5.70 ± 3.17 3.00 ± 2.45 8.70 ± 3.59
Min; Max 1; 5 5; 16 7; 19 3; 12 0; 7 3; 12
2–4 years ALL (n:14) Mean ± SD 1.00 ± 1.25 1.71 ± 2.05 2.36 ± 2.89 0.72 ± 1.81 0.127 0.64 ± 1.27 0.083 1.36 ± 2.34 0.039
Min; Max 0; 3 0; 6 0; 8 −3; 5 0; 4 −3; 6
1.1 (n:2) Mean ± SD 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0
Min; Max 0; 0 0; 0 0; 0 0; 0 0; 0 0; 0
1.5 (n:4) Mean ± SD 0.75 ± 1.50 0.25 ± 0.50 0.25 ± 0.50 −0.50 ± 1.73 0 ± 0 −0.50 ± 1.73
Min; Max 0; 3 0; 1 0; 1 −3; 1 0; 0 −3; 1
1.9 (n:8) Mean ± SD 1.38 ± 1.19 2.88 ± 2.03 4.00 ± 2.88 1.50 ± 1.77 1.13 ± 1.55 2.63 ± 2.13
Min; Max 0; 3 0; 6 0; 8 0; 5 0; 4 0; 6
5–11 years ALL (n:22) Mean ± SD 0.55 ± 1.14 0.64 ± 1.33 0.45 ± 1.01 0.09 ± 0.43 0.329 −0.18 ± 0.66 0.213 −0.09 ± 0.53 0.427
Min; Max 0; 4 0; 4 0; 4 −1; 1 −3; 0 −2; 1
1.1 (n:1) Mean ± SD 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A
Min; Max 0; 0 0; 0 0; 0 0; 0 0; 0 0; 0
1.5 (n:15) Mean ± SD 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0
Min; Max 0; 0 0; 0 0; 0 0; 0 0; 0 0; 0
1.9 (n:6) Mean ± SD 2.00 ± 1.41 2.33 ± 1.63 1.67 ± 1.37 0.33 ± 0.82 −0.67 ± 1.21 −0.33 ± 1.03
Min; Max 0; 4 0; 4 0; 4 −1; 1 −3; 0 −2; 1
12–19 years ALL (n:2) Mean ± SD 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 —
Min; Max 0; 0 0; 0 0; 0 0; 0 0; 0 0; 0
1.5 (n:1) Mean ± SD 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A
Min; Max 0; 0 0; 0 0; 0 0; 0 0; 0 0; 0
1.9 (n:1) Mean ± SD 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A 0 ± N/A
Min; Max 0; 0 0; 0 0; 0 0; 0 0; 0 0; 0