Skip to main content
. 2021 Feb 1;8(3):592–602. doi: 10.1002/acn3.51301

Figure 2.

Figure 2

The correlation between IENFD, SFN‐SIQ and COMPASS‐31 in PD patients and healthy controls (HC). (A) The IENFD and SFN‐SIQ score in G2385R carriers was comparable with that in noncarrier group, P values were 0.966 and 0.130, respectively; whereas the COMPASS‐31 score was significantly higher than noncarrier group, P = 0.044; the IENFD at distal legs was decreased in carriers and noncarrier PD compared to HC, P = 0.01; SFN‐SIQ and COMPASS‐31 scores in both groups were significantly higher than HC, both P < 0.001. Spearman correlation analysis demonstrated a moderately positive correlation between SFN‐SIQ and COMPASS31 score (B); and a mildly negative correlation IENFD and COMPASS31 score (C). Carriers n = 12, noncarriers n = 47, HC n = 30, Error bars: +SE. IENFD, intraepidermal nerve fiber density; SFN‐SIQ, small fiber neuropathy symptoms inventory questionnaire; COMPASS‐31, composite autonomic symptom score‐31 items; PD, Parkinson disease. * indicates the significant difference between two or three groups.