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. 2021 Feb 1;8(3):592–602. doi: 10.1002/acn3.51301

Figure 4.

Figure 4

The p‐syn deposition in relation to biopsy sites and the small fiber neuropathy. (A) The positivity of p‐syn deposition at C7 was significantly higher than that at DL in G2385R non‐carriers (70.2% vs. 36.2%, *P = 0.001) and whole PD group (69.5% vs. 40.7%, *P = 0.002), whereas was similar with that at DL in carriers (66.7% vs. 58.3%, P = 1.000) (chi‐square and Fisher test). (B) The IENFD, SFN‐SIQ scores or COMPASS‐31 scores of patients with or without p‐syn deposition were not significantly different (all P > 0.05) (independent‐samples T test). C7, cervical 7 region; DL, distal leg; p‐syn+, with p‐syn deposition; p‐syn‐, without p‐syn deposition; PD, Parkinson disease; IENFD, intraepidermal nerve fiber density; SFN‐SIQ, small fiber neuropathy symptoms inventory questionnaire; COMPASS‐31, composite autonomic symptom score‐31 items. Error bars: +SE.