Table 3.
Multivariable age‐adjusted associations between time seizure‐free and significant impairment or dependence in each of four functional areas and for four morbidities specifically identified by parents.
| ≥6 months versus <6 months seizure‐free in all children (N = 39) | Grouped time seizure‐free in children ≥2 years old 2 | |||||
|---|---|---|---|---|---|---|
| Odds ratio 3 | 95% (CI) | P‐value | Odds ratio 3 | 95% (CI) | P‐value | |
| Walking | 0.52 | (0.13, 2.12) | 0.36 | 0.57 | (0.22, 1.46) | 0.24 |
| Hand grasp | 0.18 | (0.04, 0.87) | 0.03 | 0.29 | (0.08, 1.05) | 0.06 |
| Feeding | 0.75 | (0.20, 2.83) | 0.67 | 0.68 | (0.25, 1.81) | 0.44 |
| Communication | 0.86 | (0.18, 4.01) | 0.85 | 0.33 | (0.07, 1.48) | 0.15 |
| # Domains with significant impairment | 0.43 | (0.13, 1.44) | 0.17 | 0.44 | (0.19, 1.03) | 0.06 |
| Constipation/dysmotility | 1.44 | (0.34, 6.09) | 0.62 | 3.13 | (0.88, 11.14) | 0.08 |
| Nights awake/week 1 | 0.25 | (0.06, 0.98) | 0.05 | 0.92 | (0.37, 2.31) | 0.87 |
| Cortical visual impairment | 0.36 | (0.09, 1.42) | 0.14 | 0.33 | (0.11, 0.93) | 0.04 |
| Autism diagnosis or features | 0.85 | (0.21, 3.34) | 0.81 | 0.94 | (0.38, 2.32) | 0.89 |
Abbreviation: CI, Confidence interval.
1
grouped as none or <1/week, 1–5/week, 6–7/week.
2
Grouped time seizure‐free: <6, 6–23, ≥24 months.
3
All estimates are adjusted for age and represent the change in the prevalence of the outcome with greater time seizure‐free.