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. 2021 Feb 5;8(3):645–655. doi: 10.1002/acn3.51308

Table 3.

Clinical course and outcome in six patients with FIRES.

Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6
Duration between IT‐DEX initiation and TPL withdrawal (days) 3 5 5 10 6 3
The period of mechanical ventilation 17 22 24 29 117 65
The day of release from ICU 20 23 28 31 71 74
Adverse effect with IT‐DEX None None None None None None
Outcome at discharge from hospital
The day of discharge from the hospital 76 87 81 149 393 94
Seizure frequency monthly weekly monthly weekly weekly annually
PCPC 3 3 2 3 4 3
Outcome at the last follow up
Seizure frequency monthly weekly none monthly weekly none
Duration of observation (months) 70 62 18 53 76 17

Abbreviations: ICU, intensive care unit; PCPC, pediatric cerebral performance category scale.