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PD-L2 is constitutively expressed in Normal Bladder tissue. (A) Representative immunohistochemistry staining of either PD-L1 or PD-L2 on normal ureter urothelium from TMAs. (B) PDCD1LG2 (PD-L2) gene expression from TCGA data from normal bladder tissue (n = 19), in comparison to all bladder cancer samples (n = 575). (C) Urinary PD-L2 levels were determined by ELISA in mid-stream urine samples from 8 healthy volunteers.
