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Why oxygen?
| Large blood vessels | Local wound |
|---|---|
| Supply oxygen to the tissue for repair and regeneration | Needed for respiration |
| Provide tissue nutrients | Neutrophil killing and other parts of host resistance versus bacteria |
| Optimise host resistance | Collagen cross linking |
| One cigarette will decrease the delivered oxygen 30% or more for an hour | Inhibit anaerobes |
| Chronic hypoxia perpetuates neutrophil infiltration |
