Table 3.

Multivariable predictions of biochemical failure by treatment, race, and PSA bounce status

		95% Confidence interval
	Hazard ratio	Lower	Upper
Panel A: Two-way interaction with race and PSA bounce
Men receiving either brachytherapy alone or in combination with EBRT
African American and PSA bounce vs. no bounce	0.69	0.44	1.07
Caucasian and PSA bounce vs. no bounce	0.79	0.59	1.05
Panel B: Three-way interactions with treatment, race, and PSA bounce
Men receiving brachytherapy alone
African American and PSA bounce vs. no bounce	0.64	0.40	1.05
Caucasian and PSA bounce vs. no bounce	0.77	0.57	1.05
Men receiving brachytherapy in combination with EBRT
African American and PSA bounce vs. no bounce	0.98	0.33	2.89
Caucasian and PSA bounce vs. no bounce	0.93	0.41	2.10

EBRT = external beam radiation therapy.

Hazard ratios generated from multivariate Cox regression model controlling for age, marital status, baseline PSA, risk group, and diagnosis year. Model with two-way interactions include an interaction term for race and PSA bounce status. Model with three-way interactions include an interaction term for treatment, race and PSA bounce status. Panel A contains a two-way interaction between race and PSA bounce. Panel B contains a three-way interaction between treatment modality, race, and PSA bounce.