Table 2.
Grade of wound inflammation at 7 and 28 days after surgical intervention (total values) (Pearson's chi squared test)
| Histopathologic scale to evaluate inflammation * | |||||||
|---|---|---|---|---|---|---|---|
| Day | Groups | Skin Total | Grade 1 | Grade 2 | Grade 3 | Grade 4 | P value |
| 7 | Wound + PRGF | 10 | 0 | 1 | 5 | 4 | 0·005 |
| Control | 10 | 0 | 6 | 4 | 0 | ||
| 28 | Wound + PRGF | 7 | 0 | 0 | 6 | 1 | 0·849 |
| Control | 9 | 0 | 0 | 18 | |||
PRGF, plasma rich in growth factors.
*Grade 1: acute inflammation (pyogenic membrane is formed); grade 2: predominance of diffuse acute inflammation (predominance of granulation tissue); grade 3: predominance of chronic inflammation (fibroblasts beginning to proliferate); grade 4: resolution and healing (reduction or disappearance of chronic inflammation, although occasional round cells may persist).
Note: Three samples of study group and one of control group were lost during the processing phase in the laboratory at 28 days.