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. 2021 Mar 11;54(4):797–814.e6. doi: 10.1016/j.immuni.2021.03.005

Figure 6.

Figure 6

COVID-19 airways contain highly elevated levels of myeloid and T cell-derived cytokines

(A) Pairwise comparison of cytokine levels averaged across both time points in airway wash and blood plasma samples collected from 15 patients. Significance indicated as p ≤ 0.05; ∗∗p ≤ 0.01; ∗∗∗p ≤ 0.001.

(B) Heatmap showing log10(mean X+1) pg/mL cytokine levels averaged across both time points in airway (left) and blood plasma (right) samples for each patient.

(C) Transcript levels for cytokine expression by major cell lineages identified by scRNA-seq for each patient samples indicated by color. Heatmap shows log2(mean CPM+1) gene expression.