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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Am J Psychiatry. 2020 Nov 10;178(2):136–155. doi: 10.1176/appi.ajp.2020.20020232

Table 1.

Glossary

Keyword Definition
Fear learning An adaptive function that allows an organism to predict potentially aversive events from environmental cues.
Unconditioned stimulus, US A stimulus that reliably produces a natural, or unconditioned, response. In fear conditioning, this stimulus is aversive in nature (e.g., shock, aversive noise).
Conditioned stimulus, CS A previously neutral stimulus that is paired with a US in classical conditioning (acquisition phase).
Fear extinction The gradual process of fear reduction in classical conditioning that involves repeated exposure to the CS without the US.
Safety learning The process of learning about safety in the environment. Tested using threat and safety discrimination.
Safety signal learning The process through which a stimulus that is overly trained to signal the absence of threat (i.e., the safety cue) reduces fear in the presence of a threatening cue.
Conditioned inhibitor A stimulus that inhibits a response as a result of learning (i.e., acquisition).
External inhibitor A stimulus that inhibits a response without having undergone explicit training.
Safety behavior An action or behavior that involves the use of a safety cue.
Preventative safety behavior An action that employs a safety behavior prior to an anticipated threatening event to avoid harm or reduce the intensity of the event.
Restorative safety behavior An action that employs a safety behavior following an aversive event with the goal of restoring safety.