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. 2021 Mar 11;16(3):e0247990. doi: 10.1371/journal.pone.0247990

Table 1. Adjuvant nomenclature and characteristics.

Vaccine Antigen (ID93) Dose Adjuvant Dose Adjuvant Description Particle Diameter of Representative Adjuvant Batch (Z-ave, nm)
ID93+SE - Stable oil-in-water emulsion 82
ID93+GLA-SE 0.5 μg 5 μg GLA GLA + stable oil-in-water emulsion 77
ID93+GLA-AF 0.5 μg 5 μg GLA GLA aqueous nanosuspension 41
ID93+LS 0.5 μg Neutral liposomes 87
ID93+LSQ 0.5 μg 2 μg QS-21 Neutral liposomes + QS-21 87
ID93+GLA-LS1 0.5 μg 5 μg GLA GLA + PEGylated liposomes 58
ID93+GLA-LSQ1 0.5 μg 5 μg GLA GLA + PEGylated liposomes + QS-21 59
2 μg QS-21
ID93+GLA-LS2 0.5 μg 5 μg GLA GLA + Anionic liposomes 73
ID93+GLA-LSQ2 0.5 μg 5 μg GLA GLA + Anionic liposomes + QS-21 70
2 μg QS-21
ID93+GLA-LS3 0.5 μg 5 μg GLA GLA + Neutral liposomes 77
ID93+GLA-LSQ3 (GLA-LSQ) 0.5 μg 5 μg GLA, 0.4, 2, or 10 μg QS-21 GLA + Neutral liposomes + QS-21 75