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. 2021 Mar 11;16(3):e0248162. doi: 10.1371/journal.pone.0248162

Table 4. Summary of the risks of bias in the MAVIE cohort and strategies for its minimization.

Bias risk or limitation Strategies
Sample size and participation bias Low response rate
  • Diversifying recruitment forms: mailing from mutual insurance, posters, media, and social networks

  • Analysis conducted excluding injuries reported on the consent date

  • Using a reference person and in particular caregivers for the elderly

  • Incidence rates standardized according to sociodemographic characteristics

Lack of representativeness
Particular interest in injury prevention or intellectual motivation
Risk of exclusion of non-users or infrequent users of the internet
Participation due to recent HLI for oneself or for a relative
Dropout Forgetting or losing interest in the study
  • Diversifying retention strategies: quarterly reminders, e-mails, monthly newsletter, online forum, smartphone application

  • Using a reference person and in particular caregivers for the elderly

Response Events under-reporting
  • Quarterly email reminders

  • One-click event reporting. Reporting possible from the smartphone application

Data are self-reported
  • Confidentiality and anonymity are guaranteed by the study investigators

  • Events are collected prospectively

Reliability of responses
  • Measuring exposures before the events report (prospective approach)

  • Involving reference persons to communicate data on the elderly

  • Assessing consistency

  • of information

Missing data
  • Questionnaires can be completed in several goes

  • Imputation in data analysis