Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 8;13(1):1893113. doi: 10.1080/19490976.2021.1893113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 6. — Fecal metabolite production is altered during a SARS-CoV-2 infection. A, SCFAs, BAs and tryptophan metabolites were measured in fecal samples from each animal and at each time point, using targeted quantitative metabolomics. Values for individual animals are presented. B, Correlations between fecal concentrations of tryptamine and serotonin. C, Correlations between fecal metabolites concentrations and plasma cytokine concentrations. Only significant correlations (p < .05) are shown. Correlations with q < 0.15 (after correction for the false discovery rate, using the Benjamini and Hochberg procedure) are indicated by an asterisk (*). TCA, taurocholic acid; GCDCA, glycochenodeoxycholic acid; LCA, lithocholic acid; CDCA, chenodeoxycholic acid; GDCA, glycodeoxycholic acid; GCA, glycocholic acid; TLCA, taurocholic acid; UDCA, ursodeoxycholic acid; CA, cholic acid; HCA, hyocholic acid; DCA, deoxycholic acid; TDCA, taurodeoxycholic acid; TCDCA, taurochenodeoxycholic acid; TRP, tryptophan; KYN, kynurenine; KA, kynurenic acid; XA, xanthurenic acid; QA, quinolinic acid; PICO, picolinic acid; 3-HAA, 3-hydroxyanthranilic Acid; CNB, cinnabarinic acid; 3-IPA, 3-Indole propionic acid; 3IS, 3-Indole sulfate; I-3 CA, Indole-3-carboxaldehyde; IAM, indole-3-acetamide; IAA, indole-3-acetic acid; ILA, indole-3-lactic acid; 5HIAA, 5-hydroxyindole acetic acid; 5HT, serotonin; 5HTP, 5-hydroxytryptophan; NasSerotonin, N-Acetylserotonin; sum_indoles, sum of all the metabolites from the indole pathway; sum_IDO, sum of all the metabolites from the IDO pathway; sum_indoles_ratio, sum of all the metabolites from the indole pathway divided by the amount of all the trypophan metabolites; sum_IDO_ratio, sum of all the metabolites from the IDO pathway divided by the amount of all the trypophan metabolites