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. 2021 Mar 1;17(3):e1009368. doi: 10.1371/journal.ppat.1009368

Fig 5. The polymorphic Asp67 in AVR-PikC disrupts hydrogen bonding between the effector and the HMA domain.

Fig 5

Close-up views of the position and interactions of Asp224 of the HMA domain in complex with either AVR-PikE (Pikp-HMA (PDB: 6G11), left) or AVR-PikC (Pikh-HMA, right). HMA domains are presented as cartoon ribbons with the side chain of Asp224 displayed as a cylinder; Pikh-HMA and Pikp-HMA are coloured in brown and ice blue, respectively. The effectors are shown in cartoon ribbon representation, with the side chains of Arg64 and Asp67/Ala67 as cylinders. AVR-PikC and AVR-PikE are coloured in crimson and bright blue, respectively. Hydrogen bonds/salt bridges are shown as black dashed lines. For clarity, the N-terminal residues 32 to 52 of the AVR-Pik effector are hidden from the foreground in both structures.