Appendix 3—table 4. Statistical frequencies of state-to-state transitions for Pol I interacting with nick- or gap-containing substrates.

	Transition frequencies
Substrate	$f_{P\to N}$	$f_{P\to U}$	$f_{N\to P}$	$f_{N\to U}$
Nick	0.4 ± 0.1	0.6 ± 0.1	0.5 ± 0.1	0.5 ± 0.1
1nt gap	0.64 ± 0.04	0.36 ± 0.04	0.67 ± 0.04	0.33 ± 0.04
2nt gap	0.6 ± 0.1	0.4 ± 0.1	0.7 ± 0.1	0.3 ± 0.1
3nt gap	0.6 ± 0.1	0.4 ± 0.1	0.66 ± 0.04	0.34 ± 0.04
4nt gap	0.54 ± 0.05	0.46 ± 0.05	0.7 ± 0.1	0.3 ± 0.1