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Melatonin alleviates ER stress during ox-LDL treatment. (a–c) HUVECs were treated with melatonin in the presence of ox-LDL. qPCR was then used to measure CHOP, GRP78, and PERK transcription. (d–g) Proteins were isolated from treated HUVECs, and expression of CHOP, GRP78, and PERK proteins was evaluated using western blots. #p < 0.05 vs. the control group, ∗p < 0.05 vs. the ox-LDL group.
