Table 4.
Diagnostic performance of Study 1 [HCC vs. others (benign and non-HCC malignant lesions)]
| Model 1 | Model 2 | |
|---|---|---|
| Accuracy (n/n) | 0.835 (313/375) | 0.840 (315/375) |
| Sensitivity (n/n) | 0.879 (175/199) | 0.804 (160/199) |
| Specificity (n/n) | 0.784 (138/176) | 0.881 (155/176) |
| PPV (n/n) | 0.822 (175/213) | 0.884 (160/181) |
| NPV (n/n) | 0.852 (138/162) | 0.799 (155/194) |
| LR+ (95% CI) | 4.073 (3.059–5.423) | 6.739 (4.485–10.125) |
| LR− (95% CI) | 0.154 (0.105–0.226) | 0.223 (0.167–0.296) |
| AUC (95% CI) | 0.903 (0.872–0.933) | N/A |
HCC, hepatocellular carcinoma; PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR−, negative likelihood ratio; CI, confidence interval; AUC, area under the curve, N/A, not applicable.