Table 5.

Diagnostic performance of Model 2 in Study 1

	Benign lesions (n = 81) vs. malignant lesions (n = 294)	HCC (n = 199) vs. non-HCC malignant lesions (n = 95)
Accuracy (n/n)	0.955 (358/375)	0.840 (247/294)
Sensitivity (n/n)	0.963 (78/81)	0.854 (170/199)
Specificity (n/n)	0.952 (280/294)	0.811 (77/95)
PPV (n/n)	0.848 (78/92)	0.904 (170/188)
NPV (n/n)	0.989 (280/283)	0.726 (77/106)
LR+ (95% CI)	20.231 (12.107–33.776)	4.508 (2.963–6.861)
LR− (95% CI)	0.039 (0.013–0.118)	0.180 (0.127–0.255)
AUC (95% CI)	0.982 (0.970–0.994)	0.880 (0.835–0.926)

HCC, hepatocellular carcinoma; PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR−, negative likelihood ratio; AUC, area under the curve; CI, confidence interval.