Table 4.
Univariate analysis of factors associated with outcomes.
| N* | Death (n = 57) | N* | RRT (n = 51) | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |||
| Patient characteristics | ||||||
| Age** | - | 1.07 (1.05–1.09) | <0.001 | - | 1.02 (0.98–1.02) | 0.823 |
| Male (yes) | 32 | 2.89 (1.50–5.55) | 0.001 | 19 | 0.49 (0.25–0.96) | 0.037 |
| TMA etiology | ||||||
| Primary TMA (vs. secondary) | 7 | 1.57 (0.59–4.16) | 0.362 | 9 | 3.00 (1.17–7.71) | 0.023 |
| TTP (yes) | 5 | 2.09 (0.63–6.86) | 0.225 | 3 | 1.08 (0.28–4.16) | 0.907 |
| aHUS or tHUS (vs. others) | 3 | 0.62 (0.17–2.27) | 0.475 | 9 | 4.84 (1.70–13.7) | 0.003 |
| HELLP syndrome (vs. others) | 0 | - | 6 | 0.17 (0.07–0.42) | <0.001 | |
| Active malignancies (vs. others) | 24 | 13.7 (5.67–33.3) | <0.001 | 7 | 0.89 (0.36–2.20) | 0.802 |
| Transplantation (vs. others) | 18 | 4.43 (2.05–9.58) | <0.001 | 10 | 1.51 (0.66–3.42) | 0.328 |
| aGvHD (vs. others) | 10 | 5.42 (1.87–15.7) | 0.002 | 2 | 0.44 (0.01–2.00) | 0.289 |
| Need for RRT (vs. no RRT) | 51 | 1.22 (0.61–2.45) | 0.576 | - | - | - |
*
Number of events in subgroup.
**
per year.