Table 1.
Characteristics of included studies
| Author | Year of publication | Journal of publication | Country | Study design | Mono-/multicentric | Study period | Sample Size (n) | Age (mean in years ± SD) | Sex (n) | Hemorrhoidal grade | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | I | II | III | IV | |||||||||
| Laser hemorrhoidoplasty | ||||||||||||||
| Karahaliloglu et al. 8 | 2007 | Coloproctology | Turkey | ORC | Monocentric | 2005 | 106 | 20–80a | - | - | 74 | 32 | 0 | 0 |
| Jahanshahi et al. 11 | 2012 | Polish Journal of Surgery | Iran | OPC | Monocentric | 2010–2011 | 341 | - | 219 | 122 | 0 | 127b | 94b | 2b |
| Brusciano et al. 12 | 2019 | Uptades in Surgery | Italy | OPC | Monocentric | 2018 | 50 | 42 ± 12.6 | 28 | 22 | 0 | 5 | 45 | 0 |
| Plapler et al. 13 | 2009 | Photomedicine and Laser Surgery | Brazil | - | Monocentric | - | 15 LH10 open HC |
25–45a - |
- | - | 0 | - | - | 0 |
| Naderan et al. 14 | 2016 | Journal of Investigative Surgery | Iran | RCT | Monocentric | 2011–2012 | 30 LH30 open HC | 43.7 ± 13.744.3 ± 11.3 | 1311 | 1719 | 0 | 1310 | 1720 | 0 |
| Alsisy et al. 15 | 2018 | Menoufia Medical Journal | Egypt | RCT | Monocentric | 2016–2017 | 30 LH30 open HC | 34.7 ± 10.233.7 ± 10.2 | 1815 | 1215 | 0 |
13 17 |
17 13 |
0 |
| Poskus et al. 16 | 2020 | International Journal of Colorectal Disease | Lithuania | RCT | Monocentric | 2016–2018 |
40 LH 41 MP 40 HC |
47 ± 13 49 ± 13 45 ± 12 |
27 22 21 |
13 19 19 |
0 |
10 10 7 |
30 31 33 |
0 |
| Hemorrhoidal laser procedure | ||||||||||||||
| Salfi et al. 9 | 2009 | Coloproctology | Italy | ORC | Monocentric | 2005–2006 | 200 | 21–81a | 72 | 128 | 0 | - | - | 0 |
| Giamundo et al. 17 | 2011 | Surgical Endoscopy | Italy | OPC | Monocentric | 2009–2010 | 30 | 47 ± 12.6 | 16 | 14 | 0 | 14 | 16c | 0 |
| Crea et al. 18 | 2014 | The American Journal of Surgery | Italy | OPC | Monocentric | 2010–2012 | 97 | 47 (28–74)d | 53 | 44 | 0 | 51 | 46c | 0 |
| De Nardi et al. 19 | 2016 | Techniques in Coloproctology | Italy | OPC | Multicentric | 2012–2014 | 51 | 44d (18–70)d | 36 | 15 | 0 | 29 | 22c | 0 |
| Boarini et al. 20 | 2017 | Journal of Inflammatory Bowel Diseases & Disorders | Brazil | OPC | Monocentric | 2011–2014 | 55 | 45.5 (22–67)d | 27 | 28 | 44 | 11c | 0 | |
| Giamundo et al. 21 | 2018 | Techniques in coloproctology | Italy | OPC | Multicentric | 2016–1017 | 284 | 47.5 (17–77)d | 183 | 101 | 5 | 174 | 101c | 4c |
| Giamundo et al. 22 | 2011 | Disease of the colon and rectum | Italy | RCT | Multicentric | 2009–2010 |
30 HeLP 30 RBL |
47d 44d |
13 12 |
17 18 |
0 |
20 19 |
10c 11c |
0 |
SD standard deviation, ORC observational retrospective cohort, “-” not available, OPC observational prospective cohort, LH laser hemorrhoidoplasty, HC hemorrhoidectomy, RCT randomized controlled trial, MP mucopexy, HeLP hemorrhoidal laser procedure, RBL rubber band ligation
aExpressed as range
b118 additional mixed grades of hemorrhoids were included
cSevere prolapses were excluded
dExpressed as median (with range)