Fig. 6. Predicted chemical shift change (absolute value in Hz, assuming 800 MHz spectrometer) caused by all possible one-nucleotide sliding in register of BP-triplets (see Supplementary Table 7 for the full list).

The data points are clearly clustered into two regions: the lower left region represents BP-triplet sliding during which the central base pair types remain the same; the middle right region represents BP-triplet sliding during which the central base pair types switch between GC and GU or between UA and UG.