Table 1.
Univariate analysis to identify factors associated with prominent vessel sign.
| Variable | Total (n = 218) |
PVS negative (n = 97) |
PVS positive (n = 121) |
P value |
|---|---|---|---|---|
| Demographics | ||||
| Age, years, median (IQR) | 67 (57–78) | 64 (55–74) | 71 (58–79) | 0.014 |
| Female, n (%) | 89 (40.8) | 36 (37.1) | 53 (43.8) | 0.318 |
| Body mass index, kg/m2, median (IQR) | 24.5 (22.1–27.2) | 24.5 (22.9–26.1) | 24.7 (21.5–27.3) | 0.984 |
| Medical history | ||||
| Hypertension, n (%) | 147 (67.4) | 68 (70.1) | 79 (65.3) | 0.451 |
| Diabetes, n (%) | 55 (25.2) | 26 (26.8) | 29 (24.0) | 0.632 |
| Coronary heart disease, n (%) | 35 (16.1) | 10 (10.3) | 25 (20.7) | 0.039 |
| Congestive heart failure, n (%) | 6 (2.8) | 2 (2.1) | 4 (3.3) | 0.888 |
| Previous ischemic stroke, n (%) | 55 (25.2) | 29 (29.9) | 26 (21.5) | 0.155 |
| Peripheral artery disease, n (%) | 6 (2.8) | 2 (2.1) | 4 (3.3) | 0.888 |
| Medication history | ||||
| Antiplatelet therapy, n (%) | 43 (19.7) | 18 (18.6) | 25 (20.7) | 0.698 |
| Stain treatment, n (%) | 34 (15.6) | 19 (19.6) | 15 (12.4) | 0.146 |
| Life style | ||||
| Smoking, n (%) | 63 (28.9) | 29 (29.9) | 34 (28.1) | 0.771 |
| Drinking, n (%) | 43 (19.7) | 24 (24.7) | 19 (15.7) | 0.096 |
| Clinical information | ||||
| Baseline NIHSS, median (IQR) | 6 (3–11) | 4 (2–8) | 9 (4–15) | < 0.001 |
| Mean arterial pressure, mmHg, mean ± SD | 110 ± 15 | 110 ± 15 | 109 ± 16 | 0.640 |
| Fasting glucose, mmol/L, median (IQR) | 7.0 (6.0–8.9) | 7.0 (6.0–8.8) | 7.0 (6.0–9.0) | 0.673 |
| Total cholesterol, mmol/L, median (IQR) | 4.2 (3.2–4.9) | 4.4 (3.3–5.1) | 3.9 (3.0–4.8) | 0.014 |
| Triglyceride, mmol/L, median (IQR) | 1.5 (1.0–2.8) | 1.8 (1.2–2.8) | 1.4 (1.0–2.7) | 0.066 |
| Hemoglobin, g/L, median (IQR) | 139 (128–151) | 144 (134–156) | 136 (125–146) | 0.001 |
| Serum creatinine, μmol/L, median (IQR) | 74.0 (62.5–86.9) | 72.0 (59.2–84.7) | 76.2 (63.3–88.2) | 0.149 |
| Time from onset to MRI, min, median (IQR) | 203 (154–272) | 214 (160–279) | 197 (151–267) | 0.420 |
| Cardioembolism | 76 (34.9) | 16 (16.5) | 60 (49.6) | < 0.001 |
| Image features | ||||
| Unilateral lesion, n (%) | 183 (83.9) | 82 (84.5) | 101 (83.5) | 0.831 |
| Anterior circulation infarct, n (%) | 159 (72.9) | 51 (52.6) | 108 (89.3) | < 0.001 |
| Large vessel occlusion, n (%) | 107 (49.1) | 7 (7.2) | 100 (82.6) | < 0.001 |
IQR interquartile range; NIHSS National Institutes of Health Stroke Scale; PVS prominent vessel sign; SD standard deviation.