Table 4.

Independent predictors of urinary albumin–creatinine ratio and estimated glomerular filtration rate in the multivariate linear regression analyses.

	Non-standardized coefficients			Standardized coefficients	r2	p value
	B	S.E	95% CI for B	B
Urinary albumin–creatinine ratio (mg/dl)a
AHI (/h)	23.3	3.8	15.9–30.7	0.460	0.212	< 0.001
Constant	− 237.6	150.8	− 535.8 to 60.5	–	–	0.117
Estimated glomerular filtration rate (eGFR) (ml/min per 1.73 m2)b
ODI (/h)	− 0.41	0.10	− 0.61 to − 0.21	− 0.324	0.105	< 0.001
Constant	70.75	4.05	62.75 to 78.74	–	–	< 0.001

AHI apnea–hypopnea index, ODI desaturation index, BMI body mass index, FMI fat mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HbA1c glycated hemoglobin, HDLc high-density lipoprotein cholesterol, LDLc low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, ACEi angiotensin-converting enzyme inhibitors, ARB angiotensin II receptor blockers, MRA aldosterone receptor antagonists, tSaO₂ < 90% percentage of recording time with oxygen saturation < 90%, SaO₂ oxygen saturation.

^aAdjusted for age, sex, BMI, FMI, duration of diabetes, smoking habit, SBP, DBP, HbA1c, cholesterol, HDLc, LDLc, triglycerides, eGFR, treatment with insulin, ACEi, ARB or MRA drugs, desaturation index, tSaO₂ < 90%, mean nocturnal SaO₂ and lowest nocturnal SaO₂.

^bAdjusted for age, sex, BMI, FMI, duration of diabetes, smoking habit, SBP, DBP, HbA1c, cholesterol, HDLc, LDLc, triglycerides, treatment with insulin, ACEi, ARB or MRA drugs, AHI, tSaO₂ < 90%, mean nocturnal SaO₂ and lowest nocturnal SaO₂.