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. 2021 Feb 26;9:644986. doi: 10.3389/fcell.2021.644986

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Copyright © 2021 Ribet, Ng and Pavlos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ins and outs of membrane transport proteins in osteoclasts. (A) Schema depicting the major types of transport proteins and their modes of substrate movement across biological membranes. (B) Model summarizing the reported membrane localization of all the major membrane transport proteins expressed in osteoclasts. Known substrates are indicated in gray. Intracellular compartments correspond to: ER, endoplasmic reticulum; SL, Secretory lysosome; LE, Late endosome; TV, Transcytotic vesicle. Created with BioRender.com.