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. 2021 Feb 26;9:643769. doi: 10.3389/fcell.2021.643769

TABLE 1.

Interactions of TOM1 family proteins.

Protein Binding partner References
TOM1 TOLLIP Yamakami et al., 2003; Katoh et al., 2004, 2006; Xiao et al., 2015
Clathrin heavy chain Yamakami et al., 2003; Katoh et al., 2006
Ubiquitin, Lys48-, Lys63-, Lys29-, and Lys33-linked polyubiquitin chains Yamakami et al., 2003; Nathan et al., 2013; Zhao et al., 2017
Endofin Seet et al., 2004; Seet and Hong, 2005
Hrs Puertollano, 2005
TSG101 Puertollano, 2005; Blanc et al., 2009
Myosin VI Tumbarello et al., 2012; Chen et al., 2019
Phosphatidylinositol 5-phosphate Boal et al., 2015; Xiong et al., 2019
TOM1-L1 Grb2* Seykora et al., 2002; Liu et al., 2009
Ubiquitin Katoh et al., 2004
TOLLIP Katoh et al., 2004, 2006
Hrs Puertollano, 2005
TSG10 Puertollano, 2005; Blanc et al., 2009
Clathrin heavy chain Katoh et al., 2006; Collin et al., 2007; Liu et al., 2009
Src kinases Collin et al., 2007
EGFR* Liu et al., 2009
p85 subunit of PI3K* Seykora et al., 2002
TOM1-L2 Clathrin heavy chain Katoh et al., 2006
TOLLIP Katoh et al., 2006
Myosin VI Tumbarello et al., 2012; Zakrzewski et al., 2020
Lys48- and Lys63-linked polyubiquitin chains Nathan et al., 2013
TOL2/6 Lys63-linked polyubiquitin chains Moulinier-Anzola et al., 2020
TOL6 ESCRT-I component VPS23A Moulinier-Anzola et al., 2020

*These proteins require Tyr phosphorylation of TOM1-L1.