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. 2021 Feb 26;12:557514. doi: 10.3389/fphys.2021.557514

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Copyright © 2021 Hagdorn, Kurakula, Koop, Bossers, Mavrogiannis, van Leusden, van der Feen, de Boer, Goumans and Berger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Myocardial remodeling and hypertrophy markers. (A–B) Ventricular weights, indexed for tibia length. (C) Representative examples of WGA-staining, on which cardiomyocyte cross-sectional area (CCSA) and capillary/myocyte ratio were determined. White bars represent 25 μm. (D–G) Summary data of CCSA and capillary/myocyte ratio. (H–K) mRNA levels of RCAN1 and FHL2. (L) Protein levels of RV pERK1/2. * represents significantly different from control, and bar represents significantly different between ACS groups.