Table 3.
Cancer type | Number of studies | Sample size | Stage I–III | Consistency | Stage IV | Consistency | I2 | Odds ratio (95% CI) | P value | ||
---|---|---|---|---|---|---|---|---|---|---|---|
C | NC | C | NC | ||||||||
Breast cancer | 3 | 890 | 458 | 267 | 63.17% | 88 | 77 | 53.33% | 38% | 1.33 (0.72, 2.47) | 0.37 |
Colorectal cancer | 5 | 1054 | 448 | 302 | 59.73% | 129 | 175 | 42.43% | 66% | 3.70 (1.93, 7.11) | < 0.0001 |
Colon cancer | 4 | 837 | 325 | 273 | 54.35% | 99 | 140 | 41.42% | 27% | 2.49 (1.50, 4.14) | 0.0004 |
Rectal cancer | 2 | 148 | 96 | 10 | 90.57% | 25 | 17 | 59.52% | 0% | 5.87 (2.36, 14.58) | 0.0001 |
Gastric cancer | 2 | 107 | 25 | 39 | 39.06% | 7 | 36 | 16.28% | 0% | 3.48 (1.28, 9.43) | 0.01 |
Lung cancer | 3 | 374 | 39 | 107 | 26.71% | 97 | 131 | 42.54% | 86% | 0.36 (0.08, 1.57) | 0.18 |
Totala | 9 | 2463 | 962 | 742 | 56.46% | 337 | 422 | 44.40% | 90% | 1.77 (0.93, 3.40) | 0.08 |
C Concordance cases, NC Nonconcordant cases.
aThe number of rectal cancer and colon cancer, which overlaps with colorectal cancer, has been excluded from the total. In addition, the total includes the number of ovarian cancer and cervical cancer.