Table 1.
Association of time period with the likelihood of lymph node dissection and the number of lymph nodes dissected in patients with vulvar squamous cell carcinoma living in northern Italy.
| Decade | Lymph node dissection (n = 760) | Number of lymph nodes dissected (n = 530)a | |||||
|---|---|---|---|---|---|---|---|
| No (n = 230) | Yes (%) (n = 530) | Odds ratio (95% CI)b | Median (range) | 1–10 (n = 93) | > 10 (%) (n = 437) | Odds ratio (95% CI)b | |
| 1980s | 38 | 78 (67.2) | 1.00 (reference category) | 19 (1–35) | 12 | 66 (84.6) | 1.00 (reference category) |
| 1990s | 65 | 117 (64.3) | 1.14 (0.66–1.96) | 19 (1–35) | 13 | 104 (88.9) | 1.48 (0.63–3.49) |
| 2000s | 69 | 172 (71.4) | 1.70 (1.00- 2.91) | 15 (1–40) | 25 | 147 (85.5) | 1.17 (0.54–2.50) |
| 2010s | 58 | 163 (73.8) | 2.03 (1.17–3.54) | 13 (1–28) | 43 | 120 (73.6) | 0.55 (0.26–1.13) |
| P = 0.061c | P = 0.000d | P = 0.005c | |||||
aAnalysis was restricted to patients undergoing lymph node dissection.
bSimultaneously adjusted for patient age, tumour size, and disease location.
cChi-square test for trend.
dKruskal-Wallis test. CI, confidence interval.