Table 2.
Association of time period with the likelihood of lymph node involvement in patients with vulvar squamous cell carcinoma living in northern Italy.
| Decade | Lymph node involvement | ||
|---|---|---|---|
| No (n = 295) | Yes (%) (n = 235) | Odds ratio (95% CI)a | |
| 1980s | 47 | 31 (39.7) | 1.00 (reference category) |
| 1990s | 68 | 49 (41.9) | 1.36 (0.72–2.60) |
| 2000s | 96 | 76 (44.2) | 1.31 (0.72–2.38) |
| 2010s | 84 | 79 (48.5) | 1.32 (0.73–2.41) |
| P = 0.16b | |||
Analysis was restricted to patients undergoing lymph node dissection (n = 530).
aSimultaneously adjusted for patient age, tumour size, disease location, depth of stromal invasion and number of lymph nodes dissected.
bChi-square test for trend. CI, confidence interval.