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. 2021 Mar 11;12:1547. doi: 10.1038/s41467-021-21685-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Representative image of PBS-injected rat ventricular myocardium, with zoomed-in image below and white arrow highlighting ICD region. b Representative image of Colch-injected rat ventricular myocardium with similar zoom and highlight as in a. c (left) Zoomed-in image of PBS-injected rat ventricular myocardium. (right) Line scan analysis of the composite image shown at bottom left. d Nuclear:cytosolic and ICD:cytosolic ratios of 18S rRNA mean fluorescence intensities of experiment depicted in a and b. PBS (N = 2), (n = 71, N/C), (n = 137, ICD/C), Colch (N = 2), (n = 92, N/C), (n = 108, ICD/C). Statistical significance determined via two sample, two-tailed t-test. For all graphs shown in figure, the mean line is shown, with whiskers denoting standard error (SE) from the mean. Source data are provided as a Source data file.