Table 2.

ROI-to-ROI functional connectivity statistics: comparisons between RW and ASD scans (ASD > RW, paired t-test, n = 28).

Target region	Abbreviation	AAL label	MNI center	t	Uncorrected p-value	FDR-corrected p-value
Left thalamus	l-Tha	Thalamus_L	–12, –18, 8
Left medial superior frontal gyrus	l-MSFG	Frontal_Sup_Med_L	−6, 49, 31	5.03	<0.001	0.003
Left middle temporal gyrus	l-MTG	Temporal_Mid_L	−57, −34, 30	−4.41	<0.001	0.007
Left orbital inferior frontal gyrus	l-OrbIFG	Frontal_Inf_Orb_L	−37, 31, −12	−3.81	<0.001	0.022
Right thalamus	r-Tha	Thalamus_R	12, −18, 8	3.35	0.002	0.045
Right inferior temporal gyrus	r-ITG	Temporal_Inf_R	53, −31, −22	−3.3	0.003	0.045
Left cuneus	l-Cun	Cuneus_L	−7, −80, 27	3.26	0.003	0.045
Left opercular inferior frontal gyrus	l-OperIFG	Frontal_Inf_Oper_L	−49, 13, 19	−3.19	0.004	0.045
Left middle temporal pole gyrus	l-MTPG	Temporal_Pole_Mid_L	−37, 15, −34	−3.12	0.004	0.047
Right calcarine	r-Cal	Calcarine_R	15, −73, 9	3.04	0.005	0.049
Left rectus	l-Rec	Rectus_L	−6, 37, −18	−3.01	0.006	0.049
Right thalamus	r-Tha	Thalamus_R	12, –18, 8
Right middle temporal gyrus	r-MTG	Temporal_Mid_R	56, −37, −1	−3.79	0.001	0.049
Left medial superior frontal gyrus	l-MSFG	Frontal_Sup_Med_L	−6, 49, 31	−3.66	0.001	0.049

ROI, region of interest; FDR, false discovery rate; ASD, Acute sleep deprivation; RW, rested wakefulness; AAL, Automated Anatomical Labeling; MNI, Montreal Neurological Institute.