Table 3.

Univariate and multivariate analyses associated to death risk with all significant variables.

VARIABLES	p-value	OR	OR 95% CI	AUC	AUC 95% CI	p-value	OR	OR 95% CI
Lymphocytes	0.018	0.2	0.05–0.076	0.77	0.634–0.873	0.027	0.15	0.02–0.81
% Th1	0.514	0.65	0.18–2.33	0.55	0.413–0.687	–	–	–
%Th17	0.085	3.8	0.83–17.37	0.63	0.495–0.761	–	–	–
% Th2	0.777	0.86	0.31–2.38	0.52	0.385–0.661	–	–	–
%Th1 PD-1-/ICOS−	0.067	0.28	0.07–10.9	0.68	0.545–0.803	–	–	–
%Th17 PD-1-/ICOS−	0.257	2.38	0.53–10.69	0.6	0.464–0.734	–	–	–
%Th2 PD-1-/ICOS−	0.259	27.778	0.47–16.35	0.618	0.451–0.766	–	–	–
% Th1 PD-1-/ICOS+	0.710	0.72	0.13–3.96	0.53	0.391–0.666	–	–	–
%Th17 PD-1-/ICOS+	0.574	1.53	0.34–6.31	0.55	0.411–0.685	–	–	–
%Th2 PD-1-/ICOS+	0.161	2.57	0.68–9.69	0.58	0.429–0.712	–	–	–
%Th1 PD-1+/ICOS+	0.631	1.79	0.14–19.46	0.52	0.384–0.659	–	–	–
%Th17 PD-1+/ICOS+	0.238	5.6	0.31–99.41	0.54	0.405–0.68	–	–	–
%Th2 PD-1+/ICOS +	0.09	0.24	0.04–1.28	0.66	0.52–0.783	–	–	–
%Th1 PD-1+/ICOS−	0.750	0.69	0.07–6.47	0.52	0.382–0.657	–	–	–
%Th17 PD-1+/ICOS−	0.073	3.86	0.87–16.97	0.656	0.514–0.780	–	–	–
%Th2 PD-1+/ICOS−	0.021	7.23	1.33–39.12	0.72	0.589–0.837	0.027	13.88	1.33–143.88
Area Under the Curve						0.879	0.760–952

PD-1-/ICOS−, Quiescent; PD-1-/ICOS+, early-activated; PD-1+/ICOS+, late-activated; PD-1+/ICOS, senescent.