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. 2021 Mar 11;11:5649. doi: 10.1038/s41598-021-85090-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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PGG apoptotic effect on (A) MM-231 and (B) MM-468 TNBC cell lines. Cells were treated with PGG (25–200 µM) and DMSO (< 0.1%) for 24 h. Annexin V-FITC kit was used, and the apoptotic effect was measured using flow cytometry. Results represent the mean ± SEM of 2 biological studies (n = 3). Differences between groups (control vs. treatments) were evaluated for statistical significance using a one-way ANOVA and Dunnett's multiple comparison tests. **p < 0.01, ***p < 0.001, ****p < 0.0001, ns = p > 0.05.