TABLE 9.

Calculated pharmacokinetic measures for psilocybin.

	Psilocybin dose (mg/kg) (mean ± SD)
	0.05 mg/kg	0.1 mg/kg	1 mg/kg	10 mg/kg
$t_{\max }$ (h)	0.6 ± 0.2	$0.32\pm 0.05$	0.36 ± 0.11	0.5 ± 0.9
$C_{\max }$ (ng/mL)	18.9 ± 9.4	$31.4\pm 15.1$	78.3 ± 15.0	3565 ± 1762
$\text{Apparent}{t}_{1/2}$ (h)	n/a	n/a	0.45 ± 0.1	0.57 ± 0.1
${\text{AUC}}_{0-t\text{last}}$ (h*ng/mL)	10.7 ± 3.2	$11.4\pm 4.5$	53.1 ± 8.9	1707 ± 884
${\text{AUC}}_{0-\inf }$ (h*ng/mL)	n/a	n/a	47.9 ± 10.2	2156 ± 1209
${\text{MRT}}_{0-\inf }\left(\text{h}\right)$	n/a	n/a	0.75 ± 0.10	0.72 ± 0.1